Cyclonite
Agent Name
Cyclonite
Alternative Name
RDX
CAS Number
121-82-4
Formula
C3-H6-N6-O6
Major Category
Other Uses
Synonyms
Cyclotrimethylenetrinitramine; Hexahydro-1,3,5-trinitro-s-triazine; Trimethylenetrinitramine; 1,3,5-Trinitro-1,3,5-triazacyclohexane; RDX; [NIOSH] UN0391
Category
Explosives
Description
White, crystalline powder. [Note: A powerful high explosive.] [NIOSH]
Sources/Uses
Used as an explosive and rodenticide; [ACGIH]
Comments
In subchronic feeding studies of dogs (50 mg/kg/day for 6 weeks), one of seven dogs died, and the others had weight loss and seizures. Methemoglobinemia was not reported. Animals in chronic studies show liver injury. Workers have experienced central nervous system effects including seizures after occupational exposure. [ACGIH]
Restricted
Transportation forbidden for Cyclonite; Transportation forbidden by passenger aircraft/rail and cargo aircraft for Cyclonite (desensitized or wetted with >15% water; [HMT]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.5 mg/m3
Vapor Pressure
4.1E-09 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
ACGIH Carcinogen
Not Classifiable
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: