Benzothiazole
Agent Name
Benzothiazole
CAS Number
95-16-9
Formula
C7-H5-N-S
Major Category
Nitrogen Compounds
Synonyms
1-Thia-3-azaindene; Benzosulfonazole; O-2857; Vangard BT; [ChemIDplus]
Category
Thiazoles
Description
Yellow liquid with an unpleasant odor; mp = 2 deg C; [HSDB] Colorless liquid; [Alfa Aesar MSDS]
Sources/Uses
Used as a flavor, antimicrobial agent, and component of cyanine dyes; Derivatives used as rubber accelerators; [HSDB] Used in organic synthesis; [Merck Index]
Comments
Not irritating to skin, but irritating to eyes of rabbits; Lethal-dose gavage study of cats produced mild methemoglobinemia and Heinz bodies in up to 100% of erythrocytes; [IUCLID] Safe when used as a flavoring agent in food; [JECFA] A mild skin and eye irritant; Causes pulmonary emboli and other changes to liver in dermal lethal-dose study of rabbits and oral lethal-dose study of rats; [RTECS] A mild skin and strong eye irritant; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.014 mm Hg
Odor Threshold Low
0.08 ppm
Odor Threshold High
0.4 ppm
Lethal Concentration
LC (rat) > 1,400 mg/m3/6h
Explanatory Notes
Odor threshold from CHEMINFO; VP from ChemIDplus;
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.