2-(tert-Butylaminothio)benzothiazole

Synonyms

2-Benzothiazolesulfenamide, N-(1,1-dimethylethyl)-; 2-Benzothiazolesulfenamide, N-tert-butyl-; Accel BNS; Benzothiazolyl-2-tert-butylsulfenamide; N-(1,1-Dimethylethyl)benzothiazolesulfenamide; N-t-Butyl-2-benzothiazolesulfenamide; N-t-Butylbenzothiazylsulfenamide; N-tert-Butyl-2-benzothiazolesulfenamide; N-tert-Butyl-2-benzothiazolyl sulfenamide; N-tert-Butyl-2-benzothiazylsulfenamide; Nocceler NS; Pennac Tbbs; Santocure NS; Santocure NS vulcanization accelerator; Vanax NS; Vulkacit NZ; [ChemIDplus]

Category

Rubber Additives

Description

Light beige solid; Sometimes blue; [HSDB] Light buff to tan powder; [MSDSonline]

Sources/Uses

Used as an accelerator for natural and synthetic isoprene rubbers and butadiene rubbers; [HSDB]

Comments

High dose oral studies with rats showed effects on the liver, kidneys, and erythrocytes (hemolysis); The LOAEL for anemia was 40 mg/kg/day by gavage; Mild irritation to skin and eyes was observed in rabbit studies; A product of hydrolysis, mercaptobenzothiazole, is a potent skin sensitizer; [eChemPortal: SIDSUNEP] A mild irritant; May cause skin sensitization; [MSDSonline] See "Mercaptobenzothiazole."

Biomedical References

Hemolytic anemia

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic