Di-sec-octyl phthalate

Synonyms

DEHP; Diethylhexyl phthalate; Di(2-ethylhexyl)phthalate; Bis(2-ethylhexyl) 1,2-benzenedicarboxylate; Bis(2-ethylhexyl) phthalate; Bis-(2-ethylhexyl)ester kyseliny ftalove [Czech]; Bisoflex 81; Bisoflex DOP; Celluflex DOP; Compound 889; DEHP; DOF [Russian plasticizer]; Di(2-ethylhexyl) orthophthalate; Di(2-ethylhexyl) phthalate; Di(2-ethylhexyl)orthophthalate; Di(2-ethylhexyl)phthalate; Diacizer DOP; Diethylhexyl phthalate; Dioctyl phthalate; Ergoplast FDO; Ergoplast FDO-S; Etalon; Etalon (plasticizer); Ethylhexyl phthalate; Eviplast 80; Eviplast 81; Fleximel; Flexol DOP; Flexol Plasticizer DOP; Good-rite GP 264; Hatcol DOP; Hercoflex 260; Jayflex DOP; Kodaflex DEHP; Kodaflex DOP; Mollan O; Monocizer DOP; Nuoplaz DOP; Octoil; PX-138; Palatinol AH; Pittsburgh PX-138; Plasthall DOP; Platinol AH; Platinol DOP; RC Plasticizer DOP; Reomol D 79P; Reomol DOP; Sansocizer DOP; Sansocizer R 8000; Sconamoll DOP; Sicol 150; Staflex DOP; Truflex DOP; Vestinol AH; Vinicizer 80; Witcizer 312; [ChemIDplus]

Category

Phthalate Esters

Description

Colorless, oily liquid with a slight odor; [NIOSH]

Sources/Uses

Used as a plasticizer; also used in pesticides (an inert ingredient), dielectric fluids, erasable inks, and vacuum pump oils; [ACGIH]

Comments

TLV Basis = "Male repro system dam; teratogenic eff;" [ACGIH TLVs and BEIs] In inhalation studies of rats, no harmful effects were found. High-dose feeding studies of mice showed reversible sperm injury; also liver damage occurred. DEHP is not readily absorbed through the skin. [ATSDR ToxFAQs] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] Occupational asthma in a PVC production worker was confirmed by PEF measurements. [Malo] Causes contact urticaria; [Kanerva, p. 219] See "PHTHALATE ESTERS."

Reference Link #1

Biomedical References

There are 5 chemicals that can be used for BEIs, measured in the urine at the end of shift; [ACGIH TLVs and BEIs]

Yes

0.1 mg/m3

5 mg/m3

2 mg/m3, inhalable fraction

5000 mg/m3

Excerpts from Documentation for IDLHs

Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for di­sec octyl phthalate. Since the acute oral toxicity data in animals [Autian 1973; Shibko and Blumenthal 1973; Yagi et al. 1976] indicates that di­sec octyl phthalate has low acute toxicity, the revised IDLH for di­sec octyl phthalate is 5,000 mg/m3 based on being 1,000 times the OSHA PEL of 5 mg/m3 . . .

1.42E-07 mm Hg

Explanatory Notes

Flash point = 405 deg F;

must be preheated

Yes

Yes

Possible (2b)

Anticipated human carcinogen

Confirmed Animal

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact urticaria

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing

Activities

Activities with risk of exposure:

• Sculpturing plastics