Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane

Synonyms

2,2'-Bis-6-terc.butyl-p-kresylmethan [Czech]; 2,2'-Methylene-bis(6-tert-butyl-4-methylphenol); 2,2'-Methylenebis(4-methyl-6-tert-butylphenol); 2,2'-Methylenebis(6-(1,1-dimethylethyl)-p-cresol); 2,2'-Methylenebis(6-tert-butyl-p-cresol); 2,2-Methylenebis(4-methyl-6-t-butylphenol); 2246; A 22-46; A-22-46; AO 1 (Antioxidant); AO 1 (VAN); AO 2246; AO1; Advastab 405; Alterungsschutzmittel BKF; Antage W 400; Anti Ox; Antioxidant 1; Antioxidant 2246; Antioxidant BKF; Antioxidant NG-2246; BKF; Bis(6-hydroxy-3-methyl-5-tert-butylphenyl)methane; Bisaklofen BP; Bisalkofen BP; CAO 14; CAO 5; Calco 2246; Catolin 14; Chemanox 21; Cyanox 2246; Di(2-hydroxy-5-methyl-3-tert-butylphenyl)methane; Lederle 2246; Methane, 2,2'-bis(6-t-butyl-p-cresyl)-; Methane, 2,2'-bis(6-tert-butyl-p-cresyl)-; Methylene bis methyl butyl phenol; NG 2246; Nocrac NS 6; Oxy Chek 114; Phenol, 2,2'-methylenebis(6-(1,1-dimethylethyl)-4-methyl-; Plastanox 2246; Plastanox 2246 Antioxidant; S 67; Sumilizer MDP; Synox 5LT; Vulkanox BKF; p-Cresol, 2,2'-methylenebis(6-tert-butyl-; [ChemIDplus]

Category

Curing Agents (Aromatic)

Description

Off-white solid; [HSDB]

Sources/Uses

Used as an antioxidant and stabilizer for polymers (ABS, polypropylene, polyacetal, rubber, latex, and adhesives); [HSDB]

Comments

Chronic high dose oral studies with rodents caused functional changes in the nervous system and liver and morphological changes to testes; [HSDB] A moderate eye irritant, based on animal studies; Although acute oral LD50 is more than 5,000 mg/kg, male reproductive effects were observed in sperm and histopathological changes to testes in test groups of 42.3 mg/kg and higher (NOAEL male reproductive toxicity = 12.2 mg/kg/day); [eChemPortal: SIDSUNEP] An eye irritant; [MSDSonline]

Biomedical References

2.5E-09 mm Hg

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing