o-Dianisidine
Agent Name
o-Dianisidine
Alternative Name
3,3`-Dimethoxybenzidine
CAS Number
119-90-4
Formula
C14-H16-N2-O2
Major Category
Nitrogen Compounds
Synonyms
1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethoxy-; 3,3'-Dianisidine; 3,3'-Dimethoxy-4,4'-diaminobiphenyl; 3,3'-Dimethoxy-4,4'-diaminodiphenyl; 3,3'-Dimethoxybenzidin [Czech]; 3,3'-Dimethoxybenzidine; 3,3'-Dimethoxybiphenyl-4,4'-diamine; 3,3'-Dimetossibenzodina [Italian]; 4,4'-Bi-o-anisidine; 4,4'-Diamino-3,3'-dimethoxybiphenyl; 4,4'-Diamino-3,3'-dimethoxydiphenyl; Acetamine Diazo Black RD; Acetamine Diazo Navy RD; Amacel Developed Navy SD; Azoene Fast Blue Base; Azofix Blue B Salt; Azogene Fast Blue B; Azogene Fast Blue B Salt; Benzidene, 3,3'-dimethoxy-; Biphenyl, 4,4'diamino-3,3'dimethoxy; Blue BN Base; Blue Base NB; Blue Base irga B; Brentamine Fast Blue B Base; C.I. 24110; C.I. Azoic Diazo Component 48; C.I. Disperse Black 6; Cellitazol B; Cibacete Diazo Navy Blue 2B; Di-p-aminodi-m-methoxydiphenyl; Diacel Navy DC; Diacelliton Fast Grey G; Dianisidine; Diato Blue Base B; Diazo Fast Blue B; Disperse Black 6; Fast Blue B Base; Fast Blue Base B; Fast Blue DSC Base; Hiltonil Fast Blue B Base; Kayaku Blue B Base; Lake Blue B Base; Meisei Teryl Diazo Blue HR; Mitsui Blue B Base; Naphthanil Blue B Base; Neutrosel Navy BN; Setacyl Diazo Navy R; Spectrolene Blue B; o-Dianisidin [Czech, German]; o-Dianisidina [Italian]; o-Dianisidine; o-Dimethoxybenzidine; ortho-Dianisidine; [ChemIDplus]
Category
Amines, Polyaromatic
Description
Colorless crystals that turn a violet color on standing; Note: Used as a basis for many dyes; [NIOSH]
Sources/Uses
Used as a chemical intermediate in the production of dyes and dianisidine diisocyanate; Also used to dye leather, paper, plastics, rubber, and textiles; [HSDB]
Comments
Causes liver injury and tumors in experimental animals; [HSDB] No published epidemiology studies on dye workers and cancer; Currently, dye production in closed systems with low risk to workers; [NTP] Classified by NIOSH as a carcinogen--reduce exposure to lowest feasible concentration; [NIOSH] "Symptoms: Irritation skin"; [CAMEO]
Biomedical References
Exposure Assessment
Explanatory Notes
Flash point = 206 deg C;
NFPA
must be preheated
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: