Dibutyl phosphate

Agent Name
Dibutyl phosphate
CAS Number
107-66-4
Formula
C8-H19-O4-P
Major Category
Other Classes
Dibutyl phosphate formula graphical representation
Synonyms
DP 4 (coupling agent); Di-n-butyl hydrogen phosphate; Di-n-butyl phosphate; Dibutyl acid phosphate; Dibutyl hydrogen phosphate; Dibutyl phosphate; Phosphoric acid, dibutyl ester; [ChemIDplus]
Category
Organophosphates, Other
Description
Pale-amber, odorless liquid; [NIOSH]
Sources/Uses
Used as an a catalyst and an antifoaming agent; [ACGIH] Used as a catalyst for resins and paints, a dielectric medium, a plasticizer (added to polymers to effect flexibility and/or toughness), a hydraulic fluid, and an antistatic in the textile industry"; [HSDB]
Comments
Workers reported respiratory irritation and headache. [ACGIH] A skin, eye, and respiratory tract irritant; [ICSC] Liver changes were found in animals fed fatal doses of 1000 mg/kg. [HSDB]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
5 mg/m3, inhalable fraction and vapor
PEL (OSHA)
5 mg/m3
IDLH (NIOSH)
30 mg/m3
Excerpts from Documentation for IDLHs
Basis for revised IDLH: Due to the lack of relevant acute toxicity data, the revised IDLH for dibutyl phosphate is 30 ppm based on an analogy to tributyl phosphate which has a revised IDLH of 30 ppm.
Vapor Pressure
9.6E-05 mm Hg
NFPA
high ambient temp required

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent