Bromophos

Synonyms

4-Bromo-2,5-dichlorophenyl dimethyl phosphorothionate; Brofene; Bromo-phos-methyl; Bromofos; Bromofos-methyl; Bromofosum [INN-Latin]; Bromovur; Brophene; Bruomophos [Russian]; Cela S 1942; Cx99; Drillzid; EL 400; ENT 27,162; Metabrom; Mexion; Monsanto CP 51969; Netal; Nexagan; Nexion; Nexion 40; Nexion 5G; Nexion LC40; O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) phosphorothioate; O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate; O,O-Dimethyl O-(4-bromo-2,5-dichlorophenyl) phosphorothioate; O,O-Dimethyl-O-(2,5-dichlor-4-bromphenyl)-thionophosphat [German]; O,O-Dimethyl-O-(2,5-dichloro-4-bromophenyl)phosphorothioate; O,O-Dimethyl-O-2,5-dichloro-4-bromophenyl phosphorothionate; O-(4-Brom-2,5-dichlor-phenyl)-O,O-dimethyl-monothiophosphat [German]; O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl monothiophosphate; O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl phosphorothioate; O-(4-Bromo-2,5-dicloro-fenil)-O,O-dimetil-monotiofosfato [Italian]; O-(4-Broom-2,5-dichloor-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch]; OMS 658; OMS-658; Omexan; Phenol, 4-bromo-2,5-dichloro-, O-ester with O,O-dimethyl phosphorothioate; Phosphorothioic acid O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester; S 1942; S-1942; Sovinexion; Thiophosphate de O,O-dimethyle et de O-4-bromo-2,5-dichlorophenyle [French; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Yellow solid; [Merck Index] Colorless solid; [MSDSonline]

Sources/Uses

Used as an insecticide and acaricide for fruit, vegetables, field crops, ornamentals, forestry, stored products, public health (i.e. flies and mosquitoes), household use, animal houses, and animal dips; [HSDB]

Comments

Depressed plasma cholinesterase was the only clinical effect found in applicators in a village in Africa; Shown to inhibit cholinesterase activity in high-dose feeding and dermal animal studies; Effects in a 100 day high-dose feeding study with rats include slow growth rates and minor degenerative damage to kidneys and liver; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

No longer registered as a pesticide for use in the US; [HSDB]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.00013 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticides, solid, toxic."

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)