Bromophos-ethyl

Synonyms

Bromofos-ethyl; Cela S 2225; ENT 27,258; Enkt 27258; Ethyl bromophos; Filariol; Nexagan; O,O-Diaethyl-O-(2,5-dichlor-4-bromphenyl)-thionophosphat [German]; O,O-Diaethyl-O-(4-brom-2,5-dichlor)-phenyl-monothiophosphat [German]; O,O-Diethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate; O,O-Diethyl O-2,5-dichloro-4-bromophenyl-phosphorothioate; O,O-Diethyl-O-(4-broom-2,5-dichloor-fenyl)-monothiofosfaat [Dutch]; O,O-Dietil-O-(4-bromo-2,5 dicloro-fenil)-monotiofosfato [Italian]; O-(4-Bromo-2,5 dichlorophenyl) O,O-diethylphosphorothionate; O-(4-Bromo-2,5-dichlorophenyl) O,O-diethyl monothiophosphate; O-(4-Bromo-2,5-dichlorophenyl) O,O-diethyl phosphorothioate; OMS-659; Phenol, 4-bromo-2,5-dichloro-, O-ester with O,O-diethyl phosphorothioate; S-2225; Thiophosphate de O,O-diethyle et de O-(2,5-dichloro-4-bromo) phenyle; Thiophosphate de O,O-diethyle et de O-(2,5-dichloro-4-bromo) phenyle [French]; Phosphorothioic acid, O-(4-bromo-2,5-dichlorophenyl) O,O-diethyl ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Colorless to pale yellow liquid; [Merck Index]

Sources/Uses

Used as acaricide, insecticide, and larvicide for fruit, vegetables, field crops, ornamentals, forestry, public health (i.e. flies and mosquitoes), animal houses, and animal dips; [HSDB]

Comments

Effects in high-dose animal studies include dyspnea, lacrimation, and convulsions; [RTECS] Besides cholinesterase inhibition, no superficial physical effects were observed in four week animal feeding studies; [INCHEM JMPR] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

No longer registered as a pesticide for use in the US; [HSDB]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

LCLo (rat) = 16.6 ppm/2h

Explanatory Notes

VP = 4.6 x10-5 mm Hg at 30 deg C; [Merck Index] The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticides, liquid, toxic."

will not burn

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)