Bromoxynil octanoate

Synonyms

2,6-Dibromo-4-cyanophenyl octanoate; 3,5-Dibromo-4-hydroxybenzonitrile octanoate; 3,5-Dibromo-4-octanoyloxy-benzonitrile; 4-Cyano-2,6-dibromophenyl octanoate; Brominal W; Bromoxynil octanoic acid ester; M&B 10731; NPH 1320; Octanoic acid ester of 3,5-dibromo-4-hydroxybenzonitrile; RP-16272; Benzonitrile, 3,5-dibromo-4-octanoyloxy-; Octanoic acid, 2,6-dibromo-4-cyanophenyl ester; [ChemIDplus]

Category

Herbicides, Other

Description

Solid; [Merck Index] Nearly white crystalline solid; [MSDSonline]

Sources/Uses

Used as herbicide for cereals, field corn, popcorn, other crops, and alfalfa in Conservation Reserve Program; [HSDB]

Comments

A mild skin and eye irritant; May cause skin sensitization; Effects in a 13 week feeding study with rats include decrease in body weight (not associated with decrease in food intake), increased kidney and liver weights, hematological changes, and myocardial degeneration and necrosis; "Four workers in a manufacturing plant making both bromoxynil and ioxynil developed typical symptoms of uncoupler poisoning including excessive perspiration, thirst, fever, emesis, myalgia, and weight loss. ... The effects reversed rapidly after exposure ceased." [HSDB] May cause skin sensitization; [eChemPortal: ESIS] May cause irritation; May cause skin sensitization; [MSDSonline] See "Bromoxynil."

Biomedical References

5 mg/m3, as CN

2 mg/m3, inhalable fraction, as CN

4.8E-06 mm Hg

LC50 (rat) = 720 mg/m3;

Reference Link #2

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Poison

Uncoupler

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Pentachlorophenol/Dinitrophenol, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)