Brucine
Agent Name
Brucine
CAS Number
357-57-3
Formula
C23-H26-N2-O4
Major Category
Biological Agents
Synonyms
(-)-Brucine; 10,11-Dimethoxystrychnine; 2,3-Dimethoxy-strychnine; 2,3-Dimethoxystrychnidin-10-one; 2,3-Dimethoxystrychnine; Brucin [German]; Brucina [Italian]; Brucine alkaloid; Brucinum; Bruzin; Dimethoxy strychnine; Strychnidin-10-one, 2,3-dimethoxy-; Strychnine, 2,3-dimethoxy-; [ChemIDplus] UN1570
Category
Plant Toxins
Description
Colorless or white odorless solid; Slightly soluble in water (3.2 g/L at 15 deg C); [HSDB] White powder; [MSDSonline]
Sources/Uses
Extracted from the seeds and bark of Strychnos aculeata; Used for denaturing alcohol and oils; Also used as an additive to lubricants, a rodent poison, a CNS stimulant, and a chemical reagent; [HSDB] A poison resembling strychnine that is much less potent; [Reference #1]
Comments
An eye, nose and throat irritant; [HSDB] Oral LD50 (mouse) = 150 mg/kg; [RTECS] May cause convulsions and respiratory paralysis; [ICSC] An irritant; Effects in high-dose animal studies include convulsions; [MSDSonline]
Reference Link #1
Biomedical References
Exposure Assessment
Vapor Pressure
3.13E-10 mm Hg
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: