Butonate
Agent Name
Butonate
CAS Number
126-22-7
Formula
C8-H14-Cl3-O5-P
Major Category
Pesticides
Synonyms
2,2,2-Trichloro-1-(dimethoxyphosphinyl)ethyl butanoate; Butanoic acid, 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester; Butilchlorofos; Butonat [German]; Butonate [ISO]; Butonato [INN-Spanish]; Butonatum [INN-Latin]; Butyric acid, ester with dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate; Dimethoxy-2,2,2-trichloro-1-n-butyryloxy-ethylphospine oxide; Dimethyl (2,2,2-trichloro-1-butyryloxyethyl)phosphonate; Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate butyric acid ester; Dimethyl 1-butyryloxy-2,2,2-trichloroethylphosphonate; Dimethyl 2,2,2-trichloro-1-n-butyryloxyethylphosphonate; ENT 20,852; ENT 20852; F 139; F-139; Fekama AT 50; O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl) phosphonate ester of butyric acid; O,O-Dimethyl (2,2,2-trichloro-1-n-butyryloxyethyl)phosphonate; O,O-Dimethyl-(1-butyryloxy-2,2,2-trichloroethyl) phosphonate; O,O-Dimethyl-(1-n-butyryloxy-2,2,2-trichloraethyl)-phosphonsaeureester; O,O-Dimethyl-2,2,2-trichloro-1-phosphonoethyl butyrate; Pedix PE 50; Pedix-50; Pedix-butonate; Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester, butyrate; T-113; Tribufon; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Colorless liquid; [HSDB]
Sources/Uses
Used as insecticide and veterinary anthelmintic (schistosoma and nematodes) and ectoparasiticide; [HSDB]
Comments
A cholinesterase inhibitor; [Hawley] No visible evidence of toxicity besides inhibition of cholinesterase activity in animal feeding studies; Not mutagenic; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Restricted
No longer registered as a pesticide for use in the US; [HSDB]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Vapor Pressure
0.000112 mm Hg
Adverse Effects
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: