1,3-Dichloropropene

Synonyms

DD-95; [Kanerva, p. 1780] DD Soil Fumigant; Telone; Vorlex; 3-Chloroallyl chloride; DCP; 1,3-Dichloro-1-propene; 1,3-Dichloropropylene; Cis-1,3-dichloropropene (10061-01-5); Trans-1,3-dichloropropene (10061-02-6);

Category

Fumigants

Description

Colorless to straw-colored liquid with a sharp, sweet, irritating, chloroform-like odor. [insecticide] [Note: Exists as mixture of cis- & trans-isomers.] [NIOSH]

Sources/Uses

Used as a soil fumigant and in organic synthesis; [ACGIH] 1,3-Dichloropropene is a mixture of cis and trans isomers used as a nematicide to fumigate soil before planting; [Reference #1]

Comments

Liquid causes first degree burns on short exposure; [CHRIS] Rats exposed to concentrations above 2700 ppm develop severe lung, nasal, liver, and kidney injury. Prolonged exposure at 1000 ppm causes unconsciousness. [ACGIH] Allergic contact dermatitis reported in farmworkers; [Kanerva, p. 1780] Can cause lacrimation; [HSDB] A potent nephrotoxin in experimental animals; [Rosenstock, p. 576] Danger of skin sensitization; [MAK]

Use as fumigant suspended by EPA due to toxicity. [Sullivan, p. 1053]

Reference Link #1

Biomedical References

Yes

1 ppm

28 mm Hg

1 ppm

Odor Threshold High

3 ppm

LCLo (rat) = 1000 ppm/2H

Explanatory Notes

Odor thresholds (detection) from CHEMINFO; VP = 34.3 mm Hg at 25 deg C (cis isomer), 23.0 mm Hg at 25 deg C (trans isomer); [HSDB]

Whole body: 1-2 days; [TDR, p. 518]

Reference Link #2

may ignite at ambient temp

Yes

Yes

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Skin burns

Possible (2b)

Anticipated human carcinogen

Confirmed Animal

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Fumigants, acute toxic effect
• Solvents, acute toxic effect