Agent Name
Propyleneimine
Alternative Name
2-Methylaziridine
Major Category
Nitrogen Compounds
Synonyms
1,2-Propyleneimine; 1,2-Propylenimine; 2-Methylazacyclopropane; 2-Methylaziridine; 2-Methylethylenimine; Aziridine, 2-methyl-; Methylaziridine; Methylethylenimine; Propilenimina [Spanish]; Propylene imine; Propyleneimine; Propylenimine; [ChemIDplus] UN1921
Category
Other Nitrogen Compounds
Description
Colorless, oily liquid with an ammonia-like odor; [NIOSH]
Sources/Uses
Used as an intermediate in the rubber and pharmaceutical industries; Used as a modifier and monomer in advanced composites; [HSDB]
Comments
At higher concentrations, may cause blistering and necrosis of the skin; Toxicity is similar to that of ethyleneimine; Causes severe injuries to the kidneys (tubular necrosis) in acute animal experiments and tumors in chronic ones; [HSDB] An irritant of the skin, eyes, and respiratory tract; [ICSC] Suspected germ cell mutagen (3B); [MAK] Propyleneimine, stabilized (UN1921) has warning of explosive polymerization; [ERG 2016]
Skin Designation (ACGIH)
Yes
Excerpts from Documentation for IDLHs
It has been reported that rats survived a 2hour exposure to 500 ppm and guinea pigs survived a 30minute exposure to 500 ppm [Carpenter et al. 1948].
Lethal Concentration
LCLo (rat) = 500 ppm/4 hr
Explosive Polymerization
Yes
Explanatory Notes
Flash point = -3 deg C; VP from HSDB;
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
ACGIH Carcinogen
Confirmed Animal
Processes
Industrial Processes with risk of exposure: