Chlorothion

Synonyms

3-Chloro-4-nitrophenyl dimethyl phosphorothioate; BAY 22190; Bayer 22/190; Chloorthion [Dutch]; Chlorthion; Chlorthion methyl; Chlortion [Czech]; Compound 22/190; Dimethyl 3-chloro-4-nitrophenyl thionophosphate; ENT 18,861; Methyl chlorothion; Methylchlorothion; O,O-Dimethyl O-(3-chloro-4-nitrophenyl) phosphorothioate; O,O-Dimethyl O-(3-chloro-4-nitrophenyl) thiophosphate; O,O-Dimethyl O-4-nitro-3-chlorophenyl thiophosphate; O,O-Dimethyl p-nitro-m-chlorophenyl thiophosphate; O,O-Dimethyl-O-(3-chlor-4-nitrophenyl)-monothiophosphat [German]; O,O-Dimethyl-O-(4-nitro-5-chlorphenyl)-thionophosphat [German]; O,O-Dimethyl-O-3-chlor-4-nitrofenylester kyseliny thiofosforecne [Czech]; O,O-Dimethyl-O-3-chlor-4-nitrofenyltiofosfat [Czech]; O-(3-Chloor-4-nitro-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch]; O-(3-Chlor-4-nitro-phenyl)-O,O-dimethyl-monothiophosphat [German]; O-(3-Chloro-4-nitrophenyl) O,O-dimethyl phosphorothioate; O-(3-Cloro-4-nitro-fenil)-O,O-dimetil-monotiofosfato [Italian]; OMS 217; Phenol, 3-chloro-4-nitro-, O-ester with O,O-dimethyl phosphorothioate; Phosphorothioic acid, O-(3-chloro-4-nitrophenyl) O,O-dimethyl ester; Thiophosphate de O,O-dimethyle et de O-3-chloro-4-nitrophenyle [French]; p-Nitro-m-chlorophenyl dimethyl thionophosphate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Yellow solid; Commercial substance is yellow liquid; [HSDB] Yellow solid; mp = 21 deg C; [MSDSonline]

Sources/Uses

Used as insecticide to control various agricultural and household pests; Also used to protect livestock and as veterinary anthelmintic; [HSDB]

Comments

A cholinesterase inhibitor; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

No longer registered as a pesticide for use in the US; [HSDB]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

4E-06 mm Hg

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)