Dichloromonofluoromethane

Synonyms

Algofrene type 5; Arcton 7; CFC-21; Dichlorofluoromethane; Dichloromonofluoromethane; Dwuchlorofluorometan [Polish]; F 21; FC-21; Fluorocarbon 21; Fluorodichloromethane; Freon 21; Freon F 21; Genetron 21; HCFC 21; Halon 112; Methane, dichlorofluoro-; Monofluorodichloromethane; R 21 (refrigerant); Racon 21; Refrigerant 21; [ChemIDplus] UN1029

Category

Chlorofluorocarbons

Description

Colorless gas with a slight, ether-like odor; Note: A liquid below 48 degrees F. Shipped as a liquefied compressed gas; [NIOSH]

Sources/Uses

CFC-21 has been used as a solvent, refrigerant, and propellant. [ACGIH]

Comments

See "CHLOROFLUOROCARBONS"; Possible frostbite from contact with liquid; [NIOSH] Inhalation of high concentrations may cause CNS effects; [ICSC] "The substance may have effects on the liver." [ICSC]

See CHLOROFLUOROCARBONS

Biomedical References

Insufficient data

10 ppm

1000 ppm

10 ppm

5000 ppm

Excerpts from Documentation for IDLHs

In 5­minute cardiac sensitization screening tests, 2 of 12 unanesthetized dogs exposed to 10,000 ppm of dichloromonofluoromethane plus intravenous epinephrine showed evidence of serious arrhythmia; no response was noted at 5,000 ppm [Mullin 1975].

LC50 (rat) = 49,900 ppm/4H

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Poison

Simple Asphyxiant

Diseases

Occupational diseases associated with exposure to this agent:

• Asphyxiation, simple
• Solvents, acute toxic effect