Convallatoxin
Agent Name
Convallatoxin
CAS Number
508-75-8
Formula
C29-H42-O10
Major Category
Biological Agents
Synonyms
3beta-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide; Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-; Convallaotoxin; Convallaton; Convallatoxoside; Convallotoxin; Corglycon; Corglycone; Corglykon; Korglykon; Mannopyranoside, strophanthidin-3,6-deoxy-, alpha-L-; Rhamnoside, strophanthidin-3, alpha-L-; Strophanthidin alpha-L-rhamnoside; Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside); [ChemIDplus]
Category
Plant Toxins
Description
Solid; [Merck Index]
Sources/Uses
Naturally occurring in lily of the valley blossoms; Used as a cardiotonic and veterinary diuretic; [Merck Index]
Comments
Emergency treatment: "Cardiac glycosides"; [HSDB] A review of 2693 lily of the valley exposures (93% children) found no fatalities with only 3 patients suffering a major outcome.[Ford, p. 924] Acute overdose of cardiac glycosides can cause vomiting, hyperkalemia, and arrhythmias. Chronic poisoning can cause visual disturbances, weakness, and arrhythmias. [Olson, p. 222-3] Oral LD50 (mouse) >2000 mg/kg; [RTECS] May cause irritation; Targets the cardiovascular system; [MSDSonline]
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.