Coumatetralyl

Agent Name
Coumatetralyl
CAS Number
5836-29-3
Formula
C19-H16-O3
Major Category
Pesticides
Coumatetralyl formula graphical representation
Synonyms
2H-1-Benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-; 3-(1,2,3,4-Tetrahydro-1-naphthyl)-4-hydroxycumarin [German]; 3-(1,2,3,4-Tetrahydro-1-naphtyl)-4-hydroxycoumarine [French]; 3-(alpha-Tetral)-4-oxycoumarin; 3-(alpha-Tetralyl)-4-hydroxycoumarin; 3-(d-Tetralyl)-4-hydroxycoumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naftyl)-cumarine [Dutch]; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-benzopyran-2-one (8CI)(9CI); 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-cumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin; 4-Idrossi-3-(1,2,3,4-tetraidro-1-naftil)-cumarina [Italian]; BAY 25634; BAY ENE 11183 B; Bayer 25 634; Coumarin, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-; Cumatetralyl [German, Dutch]; ENE 11183 B; Endox; Endrocid; Endrocide; Racumin; Raucumin 57; Rodentin; [ChemIDplus] UN3027
Category
Rodenticides, Anticoagulant
Description
Yellowish-white odorless solid; Colorless when pure; [CAMEO] Colorless powder; [MSDSonline]
Sources/Uses
Used as anticoagulant rodenticide; Not currently produced or used in the US; [HSDB]
Comments
A vitamin K antagonist--causes clotting factor disruption and bleeding; Absorbed through skin; [HSDB] First generation anticoagulant rodenticide; [INCHEM] Registered for use in the EU; Not irritating to skin or eyes of rabbits; Not sensitizing to skin of guinea pigs; No evidence of mutagenic effects; No evidence of teratogenicity in rats or rabbits (although all anti-vitamin K rodenticides classified by this commission “May cause harm to the unborn child” based on the known human developmental toxicity of Warfarin); The commercial product Racumin® Paste showed potential for skin sensitization in a Magnusson and Kligman study; [eChemPortal: ESIS] See "Warfarin."
Restricted
Not registered as a pesticide for use in the US; [HSDB]
Biomedical References

Exposure Assessment

Vapor Pressure
6.38E-11 mm Hg
Lethal Concentration
LC50 (rat) = 39 mg/m3/4h
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, toxic."

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: