Coumatetralyl

Synonyms

2H-1-Benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-; 3-(1,2,3,4-Tetrahydro-1-naphthyl)-4-hydroxycumarin [German]; 3-(1,2,3,4-Tetrahydro-1-naphtyl)-4-hydroxycoumarine [French]; 3-(alpha-Tetral)-4-oxycoumarin; 3-(alpha-Tetralyl)-4-hydroxycoumarin; 3-(d-Tetralyl)-4-hydroxycoumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naftyl)-cumarine [Dutch]; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-benzopyran-2-one (8CI)(9CI); 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-cumarin; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin; 4-Idrossi-3-(1,2,3,4-tetraidro-1-naftil)-cumarina [Italian]; BAY 25634; BAY ENE 11183 B; Bayer 25 634; Coumarin, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-; Cumatetralyl [German, Dutch]; ENE 11183 B; Endox; Endrocid; Endrocide; Racumin; Raucumin 57; Rodentin; [ChemIDplus] UN3027

Category

Rodenticides, Anticoagulant

Description

Yellowish-white odorless solid; Colorless when pure; [CAMEO] Colorless powder; [MSDSonline]

Sources/Uses

Used as anticoagulant rodenticide; Not currently produced or used in the US; [HSDB]

Comments

A vitamin K antagonist--causes clotting factor disruption and bleeding; Absorbed through skin; [HSDB] First generation anticoagulant rodenticide; [INCHEM] Registered for use in the EU; Not irritating to skin or eyes of rabbits; Not sensitizing to skin of guinea pigs; No evidence of mutagenic effects; No evidence of teratogenicity in rats or rabbits (although all anti-vitamin K rodenticides classified by this commission “May cause harm to the unborn child” based on the known human developmental toxicity of Warfarin); The commercial product Racumin® Paste showed potential for skin sensitization in a Magnusson and Kligman study; [eChemPortal: ESIS] See "Warfarin."

Not registered as a pesticide for use in the US; [HSDB]

Biomedical References

6.38E-11 mm Hg

LC50 (rat) = 39 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, toxic."

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)