Cyanophos

Synonyms

(O-p-Cyanophenyl-O,O-dimethylphosphorothioate); 4-(Dimethoxyphosphinothioyloxy)benzonitrile; BAY 34727; Bayer 34727; CYAP; Ciafos; Cyanox; Cynock; ENT 25,675; May & Baker S-4084; O,O-Dimethyl O-(4-cyanophenyl) thionophosphate; O,O-Dimethyl O-4-cyanophenyl phosphorothioate; O,O-Dimethyl O-4-cyanophenyl thiophosphate; O,O-Dimethyl phosphorothioate O-ester with p-hydroxybenzonitrile (8CI); O,O-Dimethyl-O-(4-cyano-phenyl)-monothiophosphat [German]; O,O-Dimethyl-O-p-cyanophenyl phosphorothioate; O-(4-Cyanophenyl) O,O-dimethyl phosphorothioate; O-p-Cyanophenyl O,O-dimethyl phosphorothioate; OMS 226; OMS 869; S 4084; Sumitomo S 4084; Phosphorothioic acid, O,O-dimethyl ester, O-ester with p-hydroxybenzonitrile; Phosphorothioic acid, O-(4-cyanophenyl) O,O-dimethyl ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Yellow to reddish-yellow transparent liquid; Rapidly decomposed by light and alkalinity; mp = 14-15 deg C; [Merck Index] Colorless liquid; [MSDSonline]

Sources/Uses

Used as insecticide for fruits, vegetables, and cotton; Also used to control public health pests (i.e. cockroaches and mosquitoes) and to protect grain; [HSDB]

Comments

A cholinesterase inhibitor; [Merck Index] Effects in high-dose animal studies include convulsions and spastic paralysis; [RTECS] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Not registered with the EPA for use as pesticide in the US; [CAMEO]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.000788 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticides, liquid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)