Agent Name
Difluorodibromomethane
Synonyms
Difluorodibromomethane; Fluorocarbon 12-B2; Freon 12-B2; Halon 1202; Methane, dibromodifluoro-; R 12B2; [ChemIDplus] UN1941
Category
Chlorofluorocarbons
Description
Colorless, heavy liquid or gas (above 76 degrees F) with a characteristic odor; [NIOSH]
Sources/Uses
Has been used in fire extinguishers and as a chemical intermediate; [ACGIH]
Comments
Pulmonary damage is noted in animals after a single exposure of 4000 ppm. Decomposition may yield hydrogen bromide and hydrogen fluoride; TLV Basis = irritation of upper respiratory tract, liver damage, and CNS impairment; [ACGIH] See "CHLOROFLUOROCARBONS."
Restricted
See CHLOROFLUOROCARBONS
Skin Designation (ACGIH)
Insufficient data
Excerpts from Documentation for IDLHs
Other animal data: It has been reported that 4,000 ppm for 15 minutes caused significant pulmonary damage in rats [Chambers et al. 1950]. Fatalities were noted in rats after exposures of to 2,300 ppm for 6 hours/day, 5 days/week for 7 weeks [Comstock et al. 1953]. \
Human data: None relevant for use in determining the revised IDLH.
Lethal Concentration
LC50 (mice) = 140,000 mg/m3/2H
Explanatory Notes
VP from HSDB; 2024 Notice of Intended Changes (NIC); [ACGIH TLVs and BEIs]
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases
Occupational diseases associated with exposure to this agent: