Dinobuton

Synonyms

Dessin; (2-sek.Butyl-4,6-dinitrofenyl)-isopropylkarbonat [Czech]; 1-Methylethyl 2-(1-methylpropyl)-4,6-dinitrophenyl carbonate; 2,4-Dinitro-6-sec-butylphenyl isopropyl carbonate; 2,4-Dinitro-6-sek.butyl-isopropylphenylcarbonat [German]; 2-(1-Methyl-2-propyl)-4,6-dinitrophenyl isopropylcarbonate; 2-sec-Butyl-4,6-dinitrophenyl isopropyl carbonate; Acrex; Akrex; Carbonic acid, 1-methylethyl 2-(1-methylpropyl)-4,6-dinitrophenyl ester; Carbonic acid, 2-sec-butyl-4,6-dinitrophenyl isopropyl ester; DS 18302; Dinitro-sec-butylphenyl isopropyl carbonate; Dinofen; Drawinol; ENT 27,244; Isophen (pesticide); Isopropyl 2,4-dinitro-6-sec-butylphenyl carbonate; Isopropyl-2-(1-methyl-n-propyl)-4,6-dinitrophenyl carbonate; Kasebon; MC 1053; OMS 1056; Phenol, 2-sec-butyl-4,6-dinitro-, isopropylcarbonate; Sytasol; Talan; UC 19786; Union Carbide 19786; [ChemIDplus] UN2779

Category

Other Insecticides

Description

Pale yellow solid; [HSDB] Yellowish crystalline solid; [MSDSonline]

Sources/Uses

Used as non-systemic acaricide, fungicide, and miticide; [HSDB]

Comments

A metabolic stimulant that causes weight loss in high-dose animal studies; NOAEL for dogs is 4.5 mg/kg daily; [HSDB] One of the nitrocresolic compounds that can cause fatal poisonings after dermal contamination; Effects include uncoupling oxidative phosphorylation, acute hyperthermia, liver and kidney injury, and yellow staining of skin; [EPA Pesticides, p. 104-5] May cause irritation, GI disturbances, and cyanosis; May cause injury to cardiovascular system, kidneys, and liver; [MSDSonline] See "Dinocap."

Biomedical References

1.1E-06 mm Hg

LC50 (rat) = 80 mg/m3/4h

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Substituted nitrophenol pesticide, solid, toxic."

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Other Poison

Uncoupler

Diseases

Occupational diseases associated with exposure to this agent:

• Acute tubular necrosis
• Pentachlorophenol/Dinitrophenol, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)