Agent Name
Diallyl disulfide
Major Category
Other Classes
Synonyms
2-Propenyl disulfide; 2-Propenyl disulphide; 4,5-Dithia-1,7-octadiene; Allyl disulfide; Allyl disulphide; Di(2-propenyl) disulfide; Diallyl disulphide; Disulfide, di-2-propenyl; [ChemIDplus] UN1993
Category
Sulfur Compounds
Description
Liquid with a garlic odor; [HSDB] Colorless liquid with a garlic-like stench; [Alfa Aesar MSDS]
Sources/Uses
Major constituent of garlic oil; [ChemIDplus] Used as synthetic flavoring ingredient; [HSDB] Constitutes 86.9% of diallyl disulfides (DADs) which is 90% active ingredient of biopesticide used to control white rot (fungal pathogen) in onions, garlic, and leeks; DADs are volatile sulfur compounds found in garlic, onions, and other members of Allium species; [EPA]
Comments
One of the volatiles in onions responsible for lacrimation; Emergency treatment: Irritants; [HSDB] One of the major allergens in garlic and onions; [Kanerva, p. 1777] Diallyl disulfides (DADs): A moderate eye and strong skin irritant in rabbits; A skin sensitizer in guinea pigs using the Buehler method; Causes breathing abnormalities, wobbly gait, and decreased activity in oral lethal-dose studies of rats; Oral LD50 (rat) = 346 mg/kg; Dermal LD50 (rat) = 1,967 mg/kg; [EPA] Safe when used as a flavoring agent in food; [JECFA] A moderate skin and severe eye irritant; Causes hemolysis in oral lethal-dose study of rats; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS]
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Flammable liquid, n.o.s."
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: