Dipropylene glycol methyl ether

Agent Name
Dipropylene glycol methyl ether
Alternative Name
DPGME
CAS Number
34590-94-8
Formula
C7-H16-O3
Major Category
Solvents
Dipropylene glycol methyl ether formula graphical representation
Synonyms
(2-Methoxymethylethoxy)propanol; Arcosolv DPM; Dipropylene glycol methyl ether; Dipropylene glycol monomethyl ether; Dowanol DPM; Dowanol-50B; Glysolv DPM; Kino-red; PPG-2 methyl ether; Ucar solvent 2LM; [ChemIDplus]
Category
Glycol Ethers (P Series)
Description
Colorless liquid with a mild, ether-like odor; [NIOSH]
Sources/Uses
Used in hydraulic fluids and as a solvent. [ACGIH]
Comments
Central nervous system depression observed in animal studies; TLV Basis: liver effects and CNS effects; No liver effects when animals exposed to up to 200 ppm for 13 weeks; [ACGIH] An eye and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] See "Glycol ethers."
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
No
TLV (ACGIH)
50 ppm
PEL (OSHA)
100 ppm
MAK
50 ppm, mixture of isomers
IDLH (NIOSH)
600 ppm
Excerpts from Documentation for IDLHs
Concentrations between 300 and 400 ppm have been reported to be very disagreeable [Rowe et al. 1954]. Central nervous system impairment (undefined) occurred at 1,000 ppm in one of two subjects [Stewart et al. 1970]. . . .Concentrations above 5,000 ppm are unlikely to be encountered in the workplace because of the high boiling point and low vapor pressure of this substance.
Vapor Pressure
0.3 mm Hg
Odor Threshold Low
35 ppm
Explanatory Notes
Odor threshold from CHEMINFO; Flash point = 85 deg C; VP from HSDB;
NFPA
high ambient temp required

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: