Agent Name
CAS Number
Major Category
Disulfiram formula graphical representation
1,1'-Dithiobis(N,N-diethylthioformamide); Abstensil; Abstensyl (Argentina); Abstinil; Abstinyl; Accel TET; Accel TET-R; Alcophobin; Alk-aubs; Antabus; Antabuse; Antadix; Antaenyl; Antaethyl; Antaetil; Antalcol; Antetan; Antetil; Anteyl; Anti-ethyl; Antiaethan; Anticol; Antietanol; Antietil; Antikol; Antivitium; Antivitium (Spain); Aversan; Averzan; Bis((diethylamino)thioxomethyl) disulfide; Bis((diethylamino)thioxomethyl)disulphide; Bis(N,N-diethylthiocarbamoyl) disulfide; Bis(N,N-diethylthiocarbamoyl)disulphide; Bis(diethylthiocarbamoyl) disulfide; Bis(diethylthiocarbamoyl)disulphide; Bonibal; Contralin; Contrapot; Cronetal; Dicupral; Disetil; Disulfan; Disulfiram; Disulfirame [DCIT]; Disulfiramo [INN-Spanish]; Disulfiramum [INN-Latin]; Dupon 4472; Dupont fungicide 4472; Ekagom DTET; Ekagom TEDS; Ekagom TETDS; Ephorran; Esperal [France]; Etabus; Ethyl TUEX; Ethyl thiram; Ethyl thiurad; Ethyl tuads; Ethyldithiourame; Ethyldithiurame; Exhorran; Formamide, 1,1'-dithiobis(N,N-diethylthio-; HOCA; HocakrotenalKrotenal; N,N,N',N'-Tetraethylthiuram disulfide; N,N,N',N'-Tetraethylthiuram disulphide; Nocbin; Nocceler TET; Nocceler TET-G; Noxal; Noxal (VAN); Refusal; Refusal [Netherlands]; Ro-Sulfiram; Ro-Sulfram-500 (USA); Sanceler TET; Sanceler TET-G; Soxinol TET; Stopetyl; TATD; TETD; TTD; TTS; Tenurid; Tenutex; Tetidis; Tetradine; Tetraethylthioperoxydicarbonic diamide; Tetraethylthiram disulfide; Tetraethylthiram disulphide; Tetraethylthiuram disulfide; Tetraethylthiuram disulphide; Tetraethylthiuran disulfide; Tetraethylthiurium disulfide; Tetraetil; Teturam; Teturamin; Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetraethyl-; Thiosan; Thioscabin; Thiuram E; Thiuram disulfide, tetraethyl-; Thiuranide; Tiuram; Tuads, ethyl; [ChemIDplus]
Dithiocarbamates (Pesticide)
White, yellowish, or light-gray powder with a slight odor.(fungicide); [NIOSH]
Used as a fungicide, a rubber accelerator, and a drug to treat alcoholism; [ACGIH]
Disulfiram is tested in the standard allergen tray as one of the components of the thiuram mix (tetraethylthiuram disulfide); Thiuram-sensitive patients who take Antabuse may develop a generalized contact dermatitis or localized hand and foot dermatitis. [Marks, p. 132] A nurse dispensing disulfiram developed contact dermatitis; [Kanerva, p. 1837] Drug-induced hepatitis has been rarely reported in patients taking therapeutic doses of Antabuse. [HSDB] Poisoning by ingestion (with alcohol): headache, flushing, hypotension, sweating, dizziness, nausea, vomiting, and diarrhea; Poisoning by ingestion (acute overdose): delirium, agitation, CNS depression; Poisoning by ingestion (chronic overdose): encephalopathy and neuropathy; [Ford, p. 591-4]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
2 mg/m3
2 mg/m3, inhalable fraction
Vapor Pressure
0.00087 mm Hg
Explanatory Notes
VP from HSDB;

Adverse Effects

Skin Sensitizer
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: