Firemaster BP-6; Biphenyl, hexabromo- (technical grade); Hexabromobiphenyl (technical grade); PBB; Polybrominated biphenyls; [ChemIDplus]
Used as flame retardants; [Sullivan, p. 766]
In animal studies, the effects are similar to those of PCBs. No human diseases have been linked to occupational exposure to polybrominated biphenyls. [Sullivan, p. 766] Listed in a table of "Chloracne-Producing Chemicals"; [Rosenstock, p. 714] There is evidence that PBBs can cause fetal loss and testicular damage in experimental animals. [ATSDR Case Studies #29] "The accepted view is that exposure to PBBs or PCBs leads to hepatic injury only when they are sufficiently contaminated with PCDFs." (PCDFs = polychlorinated dibenzofurans.) [Zimmerman, p. 395] Polybrominated biphenyls cause malignant liver tumors in feeding studies of rats and mice; [IARC] See "2,4,5,2',4',5'-Hexabromobiphenyl."
The manufacturing of PBBs stopped in the US in 1976. [ATSDR ToxFAQs]
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Anticipated human carcinogen
Occupational diseases associated with exposure to this agent: