Ethylenediamine

Synonyms

1,2-Diamino-ethaan [Dutch]; 1,2-Diamino-ethano [Italian]; 1,2-Diaminoaethan [German]; 1,2-Diaminoethane; 1,2-Ethanediamine; 1,2-Ethylenediamine; Aethaldiamin [German]; Aethylenediamin [German]; Algicode 106L; Amerstat 274; Dimethylenediamine; Ethyleendiamine [Dutch]; Ethylendiamine; Ethylene-diamine [French]; Ethylenediamine; beta-Aminoethylamine; [ChemIDplus] UN1604

Category

Amines, Aliphatic

Description

Colorless, viscous liquid with an ammonia-like odor; [NIOSH]

Sources/Uses

Used in the manufacture of chelating agents, fungicides, waxes, polyamide resins, and corrosion inhibitors. [ACGIH] Used as an emulsifier, an inhibitor in antifreeze solutions, and an additive to pharmaceuticals and textile lubricants; [Merck Index] Used in photography (color developing baths); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Liquid causes second degree burns after contact for a few minutes; [CHRIS] Corrosive to skin; [Quick CPC] Ethylenediamine is used in topical creams and suppositories, e.g., nystatin cream and aminophylline suppositories. Allergic contact dermatitis has been reported in a pharmacist and in healthcare workers. [Marks, p. 85-7] Allergic contact dermatitis in healthcare workers reported after exposure to intravenous aminophylline preparations containing ethylenediamine; [Kanerva, p. 1520] Occupational asthma reported in shellac handler and photographer; [Malo] Can cause pulmonary edema after an acute inhalation exposure; [ICSC] Danger of skin and airway sensitization; [MAK] Humans complain of nasal irritation after inhaling concentrations of 200 ppm for 5-10 minutes. [CAMEO] A lachrymator; [CHEMINFO]

Reference Link #1

Biomedical References

Yes

10 ppm

10 ppm

1000 ppm

Excerpts from Documentation for IDLHs

Other animal data: It has been reported that rats have survived an 8­hour exposure to 2,000 ppm [Smyth et al. 1951]. \ Human data: It has been reported that workers will not stay in concentrations of 2,000 ppm [UCC 1971].

12.1 mm Hg

1 ppm

Odor Threshold High

11 ppm

LCLo (rat) = 4,000 ppm/8 hr

Explanatory Notes

Odor threshold from CHEMINFO; Flash point = 93 deg F; VP from HSDB;

Reference Link #2

high ambient temp required

Yes

Yes

Yes

Yes

Skin burns

Not Classifiable

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Painting (Pigments, Binders, and Biocides)
• Photographic Processing
• Textiles (Fiber & Fabric Manufacturing)