2-Nitro-1,4-benzenediamine dihydrochloride
Agent Name
2-Nitro-1,4-benzenediamine dihydrochloride
CAS Number
18266-52-9
Formula
C6-H7-N3-O2.2Cl-H
Major Category
Nitrogen Compounds
Synonyms
1,4-Benzenediamine, 2-nitro-, dihydrochloride; p-Phenylenediamine, 2-nitro-, dihydrochloride; 2-Nitrobenzene-1,4-diamine dihydrochloride; [ChemIDplus]
Category
Other Aromatics (Nitrogen)
Comments
May potentially induce methemoglobinemia; Emergency treatment: "Paraphenylenediamine"; In sensitized individuals, p-phenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] See "p-Phenylenediamine."
Biomedical References
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.