Dimethyl p-(methylthio)phenyl phosphate

Synonyms

4-Methylthiophenyldimethyl phosphate; Allied GC-6506; Dimethyl-p-(methylthiofenyl)fosfat [Czech]; ENT 25734; Fenthion S 2145 oxon; GC 6506; HA-1200; O,O-Dimethyl O-(4-methylmercaptophenyl) phosphate; Phenol, p-(methylthio)-, dimethyl phosphate; Phosphoric acid, dimethyl 4-(methylthio)phenyl ester; Phosphoric acid, dimethyl p-(methylthio)phenyl ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Colorless liquid; [HSDB]

Sources/Uses

Used as contact and systemic insecticide and acaricide; [HSDB]

Comments

No significant reduction in cholinesterase activity in rats fed 0.35 mg/kg for ten days; [HSDB] Highly toxic cholinesterase inhibitor; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)