(E)-Crotonaldehyde

Synonyms

2-Butenal, (E)-; Aldehyde crotonique [French]; Crotonaldehyde, (E)-; (E)-2-Butenal; Topanel; Topanel CA; beta-Methyl acrolein; trans- Crotonal; trans-2-Butenal; trans-Crotonaldehyde; UN1143; [ChemIDplus]

Category

Aldehydes

Description

Water-white liquid with a pungent suffocating odor; [HSDB]

Sources/Uses

Used to make other chemicals (n-butyl alcohol, quinaldine, crotonic acid, 2-ethylhexyl alcohol, butyraldehyde, surface-active agents, resins, rubber antioxidants, textile and paper sizes, insecticides, and flavoring agents); Also used as a fuel-gas warning agent, solvent for polyvinyl chloride and purification of mineral oils, alcohol denaturant, leather tanning agent, to locate breaks and leaks in pipes, and in chemical warfare; [HSDB]

Comments

A mutagen and mild skin irritant; Causes ataxia in mice and convulsions in rats in lethal-dose inhalation studies; [RTECS] An eye, nose, pharynx, and larynx irritant; A lachrymator; [HSDB] A nasal membrane and strong eye irritant that may cause damage to the cornea; Causes lacrimation and may cause lung edema after inhalation of high concentrations; [CAMEO] A skin and respiratory tract irritant; May cause serious eye injury; [eChemPortal: ESIS] An irritant; Can be absorbed through skin; Effects in high-dose animal studies include lacrimation and convulsions; [MSDSonline] See "Crotonaldehyde."

Biomedical References

Yes

0.3 ppm

2 ppm

30 mm Hg

0.037 ppm

Odor Threshold High

1.05 ppm

LC50 (rat) = 4,000 mg/m3/30min

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Crotonaldehyde, stabilized." Odor threshold from HSDB; VP from ChemIDplus;

may ignite at ambient temp

Yes

Other CNS neurotoxin

Processes

Industrial Processes with risk of exposure:

• Leather Tanning and Processing
• Petroleum Production and Refining