sec-Hexyl acetate

Synonyms

1,3-Dimethylbutyl acetate; 1,3-Dimethylbutyl ethanoate; 1,3-Dimethylbutylester kyseliny octove [Czech]; 2-Pentanol, 4-methyl-, acetate; 4-Methyl-2-amyl acetate; 4-Methyl-2-pentanol, acetate; 4-Methyl-2-pentyl acetate; Acetic acid, 1,3-dimethylbutyl ester; Methyl amyl acetate; Methylamyl acetate; Methylisoamyl acetate; Methylisobutylcarbinol acetate; Methylisobutylcarbinyl acetate; sek.Isohexylester kyseliny octove [Czech]; [ChemIDplus] UN1233

Category

Esters (<C12)

Description

Colorless liquid with a mild, pleasant, fruity odor; [NIOSH]

Sources/Uses

Used as a lacquer solvent and fragrance; [ACGIH]

Comments

Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] TLV Basis is CNS impairment and irritation of eyes and upper respiratory tract. [ACGIH]

Biomedical References

Insufficient data

20 ppm

50 ppm

500 ppm

Excerpts from Documentation for IDLHs

Volunteers noted an unpleasant odor and irritation of the eyes and upper respiratory tract at 100 ppm [Silverman et al. 1946].

4 mm Hg

0.39 ppm

LCLo (rat) = 2,000 ppm/4H

Explanatory Notes

Odor threshold from AIHA; Flash point = 45 deg C; VP from HSDB;

high ambient temp required

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)