Hexylene glycol

Agent Name
Hexylene glycol
CAS Number
107-41-5
Formula
C6-H14-O2
Major Category
Other Classes
Hexylene glycol formula graphical representation
Synonyms
(+-)-2-Methyl-2,4-pentanediol; 1,1,3-Trimethyltrimethylenediol; 2,4-Dihydroxy-2-methylpentane; 2,4-Pentanediol, 2-methyl-; 2-Methyl pentane-2,4-diol; 2-Methyl-2,4-pentanediol; 4-Methyl-2,4-pentanediol; Diolane; Hexylene glycol; Isol; Pinakon; alpha,alpha,alpha'-Trimethyltrimethylene glycol; [ChemIDplus]
Category
Alcohols and Polyols, Other
Description
Colorless liquid with a mild, sweetish odor; [NIOSH]
Sources/Uses
Used as a solvent plasticizer in paints and lacquers; Also used in the chemical, petroleum refining, and cosmetic industries and as an additive to hydraulic fluids, inks, cement, leather, paper, and textiles; [ACGIH]
Comments
At 1000 ppm for 5 minutes, human subjects complain of eye, throat, and respiratory irritation. Oral dosing causes central nervous system depression in experimental animals. "Limited animal and human data suggesting a potential for skin sensitization were insufficient to support a DSEN notation." [ACGIH] Allergic contact dermatitis may occur; [Reference #1] A skin, eye, and respiratory tract irritant; [ICSC]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
25 ppm, vapor fraction
STEL (ACGIH)
50 ppm, vapor fraction
MAK
10 ppm
Vapor Pressure
0.07 mm Hg
Odor Threshold Low
3.93 ppm
Lethal Concentration
LC50 (rat) > 310 mg/m3/1h
Explanatory Notes
Flash point = 93 deg C, closed cup; Odor threshold of 3.93 reported; [ACGIH] VP from HSDB;
Reference Link #2
NFPA
must be preheated

Adverse Effects

Skin Sensitizer
Yes
Neurotoxin
Acute solvent syndrome

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: