Erucic acid
Agent Name
Erucic acid
CAS Number
112-86-7
Formula
C22-H42-O2
Major Category
Other Classes
Synonyms
13-cis-Docosenoic acid; Hystrene 2290; Z-13-Docosenoic acid; cis-13-Docosenoic acid; delta13-cis-Docosenoic acid; delta13:14-Docosenoic acid; (Z)-Docos-13-enoic acid; 13-Docosenoic acid, (13Z)-; 13-Docosenoic acid, (Z)-; [ChemIDplus]
Category
Organic Acids
Description
Solid; mp = 33.8 deg C; [Merck Index] Fine white crystals; [MSDSonline]
Sources/Uses
Isolated from the fats and oils of mustard seed, rapeseed, and crambe seed; [Hawley] Used as lubricant additive and chemical intermediate; [HSDB]
Comments
Caused asymptomatic thrombocytopenia in patients receiving Lorenzo's oil (erucic acid and oleic acid); Low platelet count reversed within 2-3 weeks of discontinuing erucic acid; Rabbits fed 40 cal% rapeseed oil versus 40 cal% sunflower oil for 84 weeks developed myocardial fibrosis, hepatic cirrhosis, and increased serum cholesterol; [HSDB] An irritant; Targets the liver and heart; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
1.15E-06 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: