2-(2,4-Diaminophenoxy)ethanol dihydrochloride
Agent Name
2-(2,4-Diaminophenoxy)ethanol dihydrochloride
CAS Number
66422-95-5
Formula
C8-H12-N2-O2.2Cl-H
Major Category
Nitrogen Compounds
Synonyms
2,4-Diaminophenoxyethanol 2HCl; 2,4-Diaminophenoxyethanol dihydrochloride; 2-(2,4-Diaminophenoxy)ethanol dihydrochloride; Ethanol, 2-(2,4-diaminophenoxy)-, dihydrochloride; [ChemIDplus] 4-(2-Hydroxyethoxy)-1,3-phenylenediamine dihydrochloride; [MSDSonline]
Category
Other Aromatics (Nitrogen)
Description
Solid; [MSDSonline] Light grey to light pink solid; [EC]
Sources/Uses
Used in hair dyes; [HSDB]
Comments
No evidence of mutagenicity; [HSDB] LD50 (gavage) in rats is approximately 1000 mg/kg; Irritating to eyes but not skin in rabbits; Not sensitizing to guinea pig skin; A moderate skin sensitizer based on local lymph node assay; Brown discoloration of the thyroid and spleen hemosiderosis observed in 13-week gavage study with rats at highest tested dose (100 mg/kg); Some evidence of mutagenicity; Teratogenic effects observed in rats (NOAEL for both maternal and embryo-fetal toxicity is 20 mg/kg/day); [EC] Harmful if swallowed; May cause skin sensitization; [Aldrich MSDS]
Biomedical References
Adverse Effects
Skin Sensitizer
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: