Etrimfos

Synonyms

ENT 29126; Ekamet; Ekamet G; Ekamet ULV; Etrimphos; O,O-Dimethyl O-(2-ethyl-4-ethoxypyriminidyl-6) thionophosphate; O,O-Dimethyl O-(2-ethyl-6-ethoxy-4-pyrimidyl)phosphorothioate; O-6-Ethoxy-2-ethylpyrimidin-4-yl O,O-dimethyl phosphorothioate; OMS 1806; Phosphorothioic acid, O-(6-ethoxy-2-ethyl-4-pyrimidinyl) O,O-dimethyl ester (9CI); SAN 197 I; SAN-I 197; SAN 197; Satisfar; Satisfar DP-2; Satisfar LS 3; Satisfar LS 5; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless liquid; [Merck Index]

Sources/Uses

Used as broad range non-systemic insecticide for fruits, vegetables, maize, ornamentals, tobacco, rice, and other crops; [HSDB]

Comments

No evidence of mutagenicity in studies using hamsters and micro organisms; No reproductive or teratogenic effects observed in three generation, two litter generation study with rats; In a reproductive study with rabbits, minor reproductive toxicity (including decrease in number of implantations and increase in dead fetuses) was observed in the highest dose groups and 3 animals born with skeletal deformations; Caused no skin and mild eye irritation in rabbits; No significant adverse effects besides inhibition of cholinesterase activity was observed in long term feeding studies with rats; No evidence of delayed neuropathy in hens nor skin sensitization in guinea pigs; [INCHEM JMPR] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

8E-05 mm Hg

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)