Isobutyl alcohol

Synonyms

1-Hydroxymethylpropane; 1-Propanol, 2-methyl-; 2-Methyl propanol; 2-Methyl-1-propanol; 2-Methylpropyl alcohol; Alcool isobutylique [French]; Fermentation butyl alcohol; Isobutanol; Isobutyl alcohol; Isobutyl alcohol (natural); Isobutylalkohol [Czech]; Isopropylcarbinol; [ChemIDplus] UN1212

Category

Alcohols (<C12)

Description

Colorless, oily liquid with a sweet, musty odor; [NIOSH]

Sources/Uses

Used as solvent in lacquers, paint removers, and liquid chromatography; used in organic synthesis; [ACGIH]

Comments

In mice, 6400 ppm produces narcosis, but not death. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Biomedical References

Insufficient data

50 ppm

100 ppm

100 ppm

1600 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Patty [1963] that 2 of 6 rats died when exposed for 4 hours to 8,000 ppm [Smyth et al. 1954]. . . . Human data: None relevant for use in determining the revised IDLH.

10.4 mm Hg

0.66 ppm

Odor Threshold High

40 ppm

1818 ppm

LCLo (rat) = 8,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 3.6 ppm); Flash point = 82 deg F; VP from HSDB;

may ignite at ambient temp

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)