Agent Name
Isopropyl alcohol
Alternative Name
2-Propanol
Synonyms
1-Methylethanol; 1-Methylethyl alcohol; 2-Hydroxypropane; 2-Propanol; 2-Propyl alcohol; Alcojel; Alcolo; Alcool isopropilico [Italian]; Alcool isopropylique [French]; Alcosolve; Alcosolve 2; Alkolave; Arquad DMCB; Avantin; Avantine; Combi-schutz; Dimethylcarbinol; Hartosol; Imsol A; Iso-propylalkohol [German]; Isohol; Isopropanol; Isopropyl alcohol; Isopropyl alcohol, rubbing; Lavacol; Lutosol; Petrohol; Propol; Spectrar; Sterisol hand disinfectant; Takineocol; Visco 1152; i-Propanol [German]; i-Propyl alcohol; i-Propylalkohol [German]; n-Propan-2-ol; sec-Propyl alcohol; [ChemIDplus] UN1219; UN1993
Description
Colorless liquid with the odor of rubbing alcohol; [NIOSH]
Sources/Uses
Used as a fuel antifreeze and an intermediate in the synthesis of organic chemicals; also used as a solvent for oils, resins, cosmetics, and many other household products; [ACGIH] Used as a disinfectant; [www.healthcouncil.nl]
Comments
Isopropyl alcohol causes narcosis in acute animal studies. [ACGIH] Isopropyl alcohol is not hepatotoxic in experimental animal studies or in human exposures. [Zimmerman, p. 367] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
BEI
Acetone in urine = 40 mg/L at end of shift at end of work week;
Skin Designation (ACGIH)
No
Excerpts from Documentation for IDLHs
Ten volunteers exposed for 3 to 5 minutes to 200, 400, or 800 ppm reported mild to moderate irritation of the eyes, nose, and throat at the two higher concentrations [Nelson et al. 1943].
Vapor Pressure
45.4 mm Hg
Odor Threshold High
610 ppm
Lethal Concentration
LC50 (rat) = 16,000 ppm/8H
Explanatory Notes
IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 43 ppm); Flash point = 12 deg C; VP from HSDB;
Half Life
Whole body: 6 hours; whole body for acetone, a metabolite: 22 hours; [TDR, p. 781]
NFPA
may ignite at ambient temp
Neurotoxin
Acute solvent syndrome
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Not Classifiable
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: