Fosthietan
Agent Name
Fosthietan
CAS Number
21548-32-3
Formula
C6-H12-N-O3-P-S2
Major Category
Pesticides
Synonyms
(Diethoxyphosphinylimino)-1,3-dithietane; 1,3-Dithietan-2-ylidenephosphoramidic acid diethyl ester; 2-(Diethoxyphosphinylimino)-1,3-dithietane; AC 64475; Acconem; CL 64475; Cyclic methylene (diethoxyphosphinyl)dithio-imidocarbonate; Cyclic methylene diethoxyphosphinodithioimidocarbonate; Cyclic methylene(diethoxyphosphinyl)dithioiminocarbonate; Diethoxyphosphinylimido-1,3-dithiethane; Diethoxyphosphinylimino-2 dithietanne-1,3 [French]; Diethyl 1,3-dithietan-2-ylidenephosphoramidate; Diethyl 1,3-dithiethane-2-ylidene-phosphoramidate; ENT 27,873; Fosthietan [ANSI]; Geofos; Imidocarbonic acid, phosphonodithio-, cyclic methylene P,P-diethyl ester (8CI); Nem-A-Tak; Phosphonodithioimidocarbonic acid cyclic methylene P,P-diethyl ester; Phosphoramidic acid, 1,3-dithietan-2-ylidene-, diethyl ester; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Pale yellow liquid; [HSDB]
Sources/Uses
Used as soil insecticide and nematicide; [HSDB]
Comments
A cholinesterase inhibitor; Can be absorbed through skin; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Restricted
Not currently registered as a pesticide for use in the US; [HSDB]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Vapor Pressure
6.45E-06 mm Hg
Adverse Effects
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: