N,N'-Bis(2-methylphenyl)guanidine
Agent Name
N,N'-Bis(2-methylphenyl)guanidine
CAS Number
97-39-2
Formula
C15-H17-N3
Major Category
Plastics & Rubber
Synonyms
1,3-Ditolylguanidine; 1,3-Bis(o-tolyl)guanidine; 1,3-Di-o-tolyguanidine; 1,3-Di-o-tolylguanidine; Akrochem DOTG; CNS 1001; DOTG; DOTG accelerator; DTG; Di-o-tolylguanidine; Diorthotolylguanidine; Eveite DOTG; Guanidine, 1,3-di(2-tolyl)-; Guanidine, 1,3-di-o-tolyl-; Guanidine, N,N'-bis(2-methylphenyl)-; N,N'-Di-o-tolueylguanidine; N,N'-Di-o-tolylguanidine; Nocceler DT; Sanceler DT; Soxinol DT; Vulcafor DOTG; Vulkacit DOTG; Vulkacit DOTG/C; Vulkacite DOTG; [ChemIDplus]
Category
Rubber Additives
Description
White solid; [Hawley] Grey or white powder; [MSDSonline]
Sources/Uses
Used as a rubber accelerator; [Hawley] Degraded during the vulcanization process, so consumers not likely to have significant exposure; [Reference #1]
Comments
A selective ligand for the sigma site in the mammalian CNS--high parenteral doses in rodents cause behavioral effects; [Reference #1] Presumed to be irritating to eye mucous membranes; [HSDB] Oral LD50 (rat) = 500 mg/kg; Oral LDLo (unspecified mammal) = 120 mg/kg (Effects included somnolence, dyspnea, and cyanosis.) [ChemIDplus] An eye irritant; [eChemPortal: ERMA] May cause irritation; [MSDSonline]
Reference Link #1
Biomedical References
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.