Methyl silicate

Synonyms

Tetramethoxysilane; MSP 150; Methyl Silicate 39; Methyl orthosilicate; Methyl silicate; Methyl silicate ((CH3)4SiO4); Methyl silicate ((MeO)4Si); Methyl silicate 28; SIT 7510.0; Silane, tetramethoxy-; Silicic acid, methyl ester of ortho-; Silicic acid, tetramethyl ester; TL 190; TMOS; TSL 8114; Tetra-methyl orthosilicate; Tetramethoxysilane; Tetramethyl silicate; Tetramethylsilikat [Czech]; [ChemIDplus] UN2606

Category

Metalloid Compounds (Silicon)

Description

Clear, colorless liquid. [Note: A solid below 28 degrees F.]; [NIOSH]

Sources/Uses

Used in corrosion resistant coatings and in catalysts; used to manufacture silicone; [ACGIH]

Comments

Severe damage to the cornea has been reported after occupational exposure. Experimental animals exposed repeatedly to 30 ppm develop respiratory disease with bronchiolar inflammation. [ACGIH] Its severe corneal toxicity is delayed by several hours, and workers have little or no immediate eye symptoms. [HSDB] Has potential to cause pulmonary edema after high inhalation exposure; May have effects on liver and kidneys; [ICSC] See "Ethyl silicate."

Biomedical References

Insufficient data

Yes

1 ppm

16.5 mm Hg

LCLo (rat) = 250 ppm/4h

Explanatory Notes

Flash point = 205 deg F; VP from HSDB;

Reference Link #2

may ignite at ambient temp

Not appropriate

10 ppm

20 ppm

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Pneumonitis, toxic