Methylcyclohexane

Synonyms

Cyclohexane, methyl-; Cyclohexylmethane;Hexahydrotoluene; Hexahydroxytoluene; Methylcyclohexane; Metylocykloheksan [Polish]; Sextone B; Toluene hexahydride; Toluene, hexahydro-; [ChemIDplus] UN2296

Category

Aliphatics, Saturated (<C12)

Description

Colorless liquid with a faint, benzene-like odor; [NIOSH]

Sources/Uses

Used in organic synthesis, as a solvent for cellulose ethers, and in jet fuel. [ACGIH]

Comments

Slight histopathological changes in the kidney and liver seen in subchronically exposed experimental animals; TLV Basis is kidney damage; [ACGIH] A skin and eye irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Biomedical References

Insufficient data

100 ppm

500 ppm

200 ppm

1200 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: With no reported human toxicological data, the chosen IDLH is based on the statement by Browning [1965] that Treon et al. [1943] were able to produce light narcosis in mice at 10,054 ppm. Browning [1965] also reported that Lazarew [1929] found the narcotic dose for mice to be 7,500 to 10,000 ppm. ACGIH [1971] noted that this narcotic dose (7,500 to 10,000 ppm) was for a 2­hour exposure [Lazarew 1929; Treon et al. 1943]. . . . Human data: None relevant for use in determining the revised IDLH.

46 mm Hg

500 ppm

LCLo (rat) = 82,000 mg/m3/1H

Explanatory Notes

IDLH = 10% LEL; Odor threshold from CHEMINFO; Flash point = -4 deg C; VP from HSDB;

may ignite at ambient temp

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect