Imperatorin

Synonyms

5-Benzofuranacrylic acid, 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-, delta-lactone; 6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3-methyl-2-butenyl)oxy)-; 8-Isoamylenoxypsoralen; 8-Isopentenyloxypsoralene; 9-((3-Methyl-2-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one; 9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one; Ammidin; Marmelosin; Pentosalen; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Solid; [Merck Index]

Sources/Uses

Found in the roots of Imperatoria osthruthium, seeds of Angelica archangelica, and fruit of Pastinaca sativa; [Merck Index] Dried substance and derivatives used in liqueurs (bitters); [HSDB] A naturally occurring psoralen; [REPROTOX]

Comments

Emergency treatment: "Psoralens"; Therapeutic doses (with UV light) are 0.6 mg/kg; Hepatitis has been reported after ingestion of herbal remedies and use of psoralen-UV therapy; [HSDB] May cause irritation; [MSDSonline] See "Angelicin."

Biomedical References

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

PICD (photoirritant contact dermatitis)

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, photoirritant