Isolan
Agent Name
Isolan
CAS Number
119-38-0
Formula
C10-H17-N3-O2
Major Category
Pesticides
Synonyms
(1-Isopropil-3-metil-1H-pirazol-5-il)-N,N-dimetil-carbammato [Italian]; (1-Isopropyl-3-methyl-1H-pyrazol-5-yl)-N,N-dimethyl-carbamat [German]; (1-Isopropyl-3-methyl-1H-pyrazol-5-yl)-N,N-dimethylcarbamaat [Dutch]; 1-Isopropyl-3-methyl-5-pyrazolyl dimethylcarbamate; 1-Isopropyl-3-methyl-5-pyrazolylester kyseliny dimethylkarbaminove [Czech]; 1-Isopropyl-3-methylpyrazolyl-(5)-dimethylcarbamate; 5-Methyl-2-isopropyl-3-pyrazolyl dimethylcarbamate; Carbamic acid, dimethyl-, 1-isopropyl-3-methylpyrazol-5-yl ester; Carbamic acid, dimethyl-, 3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl ester; Dimethyl-5-(1-isopropyl-3-methyl-pyrazolyl)-carbamate; Dimethylcarbamate d'1-isopropyl 3-methyl 5-pyrazolyle [French]; Dimethylcarbamate de 1-isopropyl 3-methyl 5-pyrazolyle [French]; Dimethylcarbamic acid 1-isopropyl-3-methylpyrazol-5-yl ester; Dimethylcarbamic acid 3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl ester; ENT 19,060; G 23611; Geigy G-23611; Isolan (pesticide); Isolane [French]; Isopropylmethylpyrazolyl dimethylcarbamate; OMS 62; Primin; Pyrazol-5-ol, 1-isopropyl-3-methyl-, dimethylcarbamate; Saolan; [ChemIDplus]
Category
Carbamate Insecticides
Description
Colorless liquid; [HSDB]
Sources/Uses
Used as a contact, systemic, and fumigant insecticide; No longer of much commercial interest; [HSDB] Used as systemic insecticide in Europe; [CAMEO]
Comments
Shown to be more toxic dermally than orally in rats; [Merck Index] A cholinesterase inhibitor; [Hawley] No increase in tumor types or frequency in 78 week feeding study with mice; Mutagenic observations in studies with Saccharomyces cerevisiae, but not with B. subtilis (no metabolic activation); [HSDB] Highly toxic cholinesterase inhibitor; [CAMEO] See "CARBAMATE INSECTICIDES."
Restricted
No longer registered as a pesticide for use in the US; [HSDB]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Vapor Pressure
0.00127 mm Hg
Adverse Effects
Other Poison
Carbamate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: