Jervine
Agent Name
Jervine
CAS Number
469-59-0
Formula
C27-H39-N-O3
Major Category
Biological Agents
Synonyms
Jervin; Jerwiny [Polish]; Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one, 2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-; Veratraman-11-one, 17,23-epoxy-3-hydroxy-, (3beta,23beta)-; 17,23beta-Epoxy-3beta-hydroxyveratraman-11-one; [ChemIDplus]
Category
Plant Toxins
Description
Solid; [Merck Index]
Sources/Uses
A steroidal alkaloid present in the genus Veratrum; [Merck Index]
Comments
Emergency treatment: "Plants- veratrum alkaloids"; Excessive amounts can cause death by central respiratory depression; Symptoms begin 1/2 to 4 hours after ingestion and usually last 24 to 48 hours. Ingestion of 4-5 bulbs for a child and 40-50 bulbs for an adult may be fatal. [HSDB] Veratrum alkaloids (e.g., black snakeroot, false hellebore, and skunk cabbage) cause gastroenteritis, bradycardia, paresthesias, AV block, and syncope;; [Olson, p. 376-92] May cause irritation; Effects in high-dose animal studies include convulsions; [MSDSonline]
Biomedical References
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.