Linalool

Synonyms

Linalyl alcohol; (+-)-Linalool; 1,6-Octadien-3-ol, 3,7-dimethyl-; 2,6-Dimethyl-2,7-octadiene-6-ol; 2,6-Dimethylocta-2,7-dien-6-ol; 3,7-Dimethyl-1,6-octadien-3-ol; 3,7-Dimethylocta-1,6-dien-3-ol; Linalool (natural); allo-Ocimenol; beta-Linalool; p-Linalool; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Colorless liquid with an odor of bergamot oil or French lavender; [Hawley]

Sources/Uses

Main component of linaloe oil; Also found in oils of Ceylon cinnamon, sassafras, orange flower, and bergamot; [Merck Index] Found in citrus peel oils (especially orange); [Hawley] Used in perfumes, fragrances, flavoring agents, household cleaners, and insecticidal pet treatments; (direct application to pet and indoor area); [HSDB]

Comments

A skin and eye irritant; May cause liver injury; [ICSC] Emergency treatment: "Linalool"; A skin and eye irritant; [HSDB] Safe to use as a flavoring agent in food; [JECFA] Slight sedative effects after inhalation; Not a sensitizer; Not mutagenic; Causes effects on liver and kidneys in 28-day rat feeding study (72.9% linalool) with a NOAEL of 160 mg/kg/day; [OECD SIDS: Linalool - 2002] Included in list of "established contact allergens in humans"; [EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)]

Biomedical References

0.16 mm Hg

1 ppm

Explanatory Notes

Olfactory threshold is approximately 1 ppm; [Reference #1]

high ambient temp required

Yes

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Solvents, acute toxic effect