Menazon

Synonyms

2,4-Diamino-6-dimethoxyphosphinothionylthiomethyl-s-triazine; 2-Dimethoxyphosphinothioylthiomethyl-4,6-diamino-s-triazine; 4,6-Diamino-1,3,5-triazin-2-ylmethyl O,O-dimethyl phosphorodithioate; Azidithion; Dithiophosphate de O,O-dimethyle et de S-((4,6-diamino-1,3,5-triazine-2-yl)-methyle) [French]; ENT 25,760; Menazon [ISO]; O,O-Dimethyl S-(4,6-diamino-1,3,5-triazin-2-yl)methyl phosphorodithioate; O,O-Dimethyl S-(4,6-diamino-1,3,5-triazin-2-yl)methyl phosphorothiolothionate; O,O-Dimethyl S-(4,6-diamino-1,3,5-triazinyl-2-methyl) dithiophosphate; O,O-Dimethyl S-(4,6-diamino-s-triazin-2-ylmethyl)phosphorodithioate; O,O-Dimethyl S-((4,6-diamino-s-triazin-2-yl)methyl) phosphorodithioate; PP175; Phosphorodithioic acid, S-((4,6-diamino-1,3,5-triazin-2-yl)methyl) O,O-dimethyl ester; Phosphorodithioic acid, S-((4,6-diamino-s-triazin-2-yl)methyl) O,O-dimethyl ester; R 15,175; S-((4,6-Diamino-1,3,5-triazin-2-yl)-methyl)-O,O-dimethyl-dithiofosfaat [Dutch]; S-((4,6-Diamino-1,3,5-triazin-2-yl)-methyl)-O,O-dimethyl-dithiophosphat [German]; S-((4,6-Diamino-1,3,5-triazin-2-yl)methyl)phosphorodithioic acid O,O-dimethyl ester; S-((4,6-Diamino-s-triazin-2-yl)methyl) O,O-dimethyl phosphorodithioate; S-((4,6-Diamino-s-triazin-2-yl)methyl) O,O-dimethylphosphorodithioate; S-((4,6-Diamino-s-triazin-2-yl)methyl)-O,O-dimethyl phosphorodithioate; S-(4,6-Diamino-1,3,5-triazin-2-ylmethyl) O,O-dimethyl phosphorodithioate; S-(4,6-Diamino-1,3,5-triazin-2-ylmethyl) dimethyl phosphorothiolothionate; Saiphos; Saphicol; Saphizon; Saphizon-DP; Sayfor; Sayfos; Sayphos; Syphos; s-Triazine-2-methanethiol, 4,6-diamino-, S-ester with O,O-dimethyl phosphorodithioate; s-Triazine-2-methanethiol, 4,6-diamino-, S-ester with O,O-dimethylphosphorodithioate; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Off-white solid; [Hawley] Colorless solid; [HSDB]

Sources/Uses

Used as acaricide and insecticide; [Hawley] Not commercially registered in the US; Likely discontinued for pesticide use worldwide; [HSDB]

Comments

Very toxic cholinesterase inhibitor; [Hawley] No significant adverse effects observed in animal studies besides inhibition of cholinesterase activity; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

9.75E-07 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, solid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)