Mephosfolan
Agent Name
Mephosfolan
CAS Number
950-10-7
Formula
C8-H16-N-O3-P-S2
Major Category
Pesticides
Synonyms
(4-Methyl-1,3-dithiolan-2-ylid-ene)phosphoramidic acid diethyl ester; (Diethoxyphosphinyl)dithioimidocarbonic acid cyclic propylene ester; 1,2-Propanedithiol, cyclic ester with P,P-diethyl phosphonodithioimidocarbonate; 2-(Diethoxyphosphinylimino)-4-methyl-1,3-dithiolane; AC 47470; American Cyanamid CL-47470; CL-47,470; Cyclic propylene (diethoxyphosphinyl)dithioimidocarbonate; Cyclic propylene P,P-diethyl phosphonodithioimidocarbonate (8CI); Cytrolane; Cytrolane insecticide; Diethyl (4-methyl-1,3-dithiolan-2-ylidene)phosphoroamidate; EI-47470; ENT-25,991; Imidocarbonic acid, phosphonodithio-, cyclic propylene P,P-diethyl ester; Mephospholan [ISO-French]; O,O-Diethyl(4-methyl-1,3-dithiolan-2-ylidene)phosphoramidate; P,P-Diethyl cyclic propylene ester of phosphonodithioimidocarbonic acid; Phosphonodithioimidocarbonic acid cyclic propylene P,P-diethyl ester; Phosphoramidic acid, (4-methyl-1,3-dithiolan-2-ylidene)-, diethyl ester; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Colorless or yellow to amber liquid; [HSDB]
Sources/Uses
Used as contact and stomach insecticide and acaricide for cotton, fruits, vegetables, maize, and other crops; [HSDB]
Comments
A highly toxic cholinesterase inhibitor; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Restricted
Not registered in the US for use as pesticide; [CAMEO]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Vapor Pressure
3.18E-05 mm Hg
Adverse Effects
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: