Methanearsonic acid

Synonyms

Arsonic acid, methyl-; DSMA (JMAF); Kyselina methylarsonova [Czech]; Methylarsonic acid [ISO]; Monomethylarsonate; Monomethylarsonic acid; [ChemIDplus] UN1557

Category

Arsenic Compounds, Organic

Description

White hygroscopic solid; [ICSC]

Sources/Uses

Used as herbicide in the past; [Merck Index] Not currently registered with the EPA for use in the US; [HSDB]

Comments

Oral LD50 (rat) = 961 mg/kg; [Sax] A mild skin, eye, and respiratory tract irritant; May cause kidney and liver injury; [ICSC] After ingestion of arsenic-rich wine, the majority of the arsenic was excreted in the urine in methylated form (methylarsonic acid & dimethylarsinic acid); Methylarsonic acid (MAA) fed to dairy cows in cottonseed ration had no apparent adverse effects; MAA was poorly absorbed and rapidly excreted in the urine; [HSDB] Arsenic is a known teratogen, but the effects of organic arsenicals is less clear. MAA is not likely to be a reproductive hazard at levels currently found in the environment; [REPROTOX] An irritant; [MSDSonline]

Biomedical References

0.5 mg/m3, as As

0.00162 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Arsenic compound, solid, n.o.s." VP from ChemIDplus;

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Possible (2b)

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)