Pindone
Agent Name
Pindone
Alternative Name
2-Pivalyl-1,3-indandione
CAS Number
83-26-1
Formula
C14-H14-O3
Major Category
Pesticides
Synonyms
tert-Butyl valone; 1,3-Dioxo-2-pivaloylindan; Pival; Pivalyl; 2-Pivalyl-1,3-indandione; [NIOSH]
Category
Rodenticides, Anticoagulant
Description
Bright-yellow powder with almost no odor. [rodenticide]; [NIOSH]
Sources/Uses
Used as an anticoagulant rodenticide and an insecticide; [ACGIH]
Comments
A vitamin K antagonist that inhibits prothrombin; [ACGIH]
Reference Link #1
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
0.1 mg/m3
PEL (OSHA)
0.1 mg/m3
IDLH (NIOSH)
100 mg/m3
Excerpts from Documentation for IDLHs
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for pindone. Therefore, the revised IDLH for pindone is 100 mg/m3 based on acute oral toxicity data in humans [Gosselin et al. 1984] and animals [Gaines 1960; Klimmer 1971; Perkow 1971/1976] and an analogy to warfarin [ACGIH 1971] which has a revised IDLH of 100 mg/m3.
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: