Methyl fluorosulfonate
Agent Name
Methyl fluorosulfonate
CAS Number
421-20-5
Formula
C-H3-F-O3-S
Major Category
Other Classes
Synonyms
Fluorosulfuric acid, methyl ester; Magic Methyl; Methyl fluorosulfate; Methyl fluosulfonate; [ChemIDplus] UN1992
Category
Other Organic Compounds
Description
Colorless liquid with an ethereal odor; [Hawley] Cloudy colorless or yellow liquid; [MSDSonline]
Sources/Uses
Used as methylating agent in organic synthesis; [Merck Index]
Comments
Extremely toxic; May cause pulmonary edema; [Merck Index] Reacts with moisture producing corrosive vapor; A strong tissue irritant; [Hawley] Evolves hydrofluoric and sulfuric acid on contact with water; [ChemIDplus] Corrosive to skin of rabbits; May cause pulmonary edema and corneal damage; Emergency treatment: see "Hydrogen fluoride." [HSDB] A mutagen; Causes lacrimation and dyspnea in lethal-dose inhalation studies of rats; [RTECS] An irritant; May cause serious eye injury; May cause pulmonary edema; [MSDSonline]
Biomedical References
Exposure Assessment
Lethal Concentration
LC50 (rat) = 5 ppm/1h
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Flammable liquid, toxic, n.o.s."
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.